Bart Classen wrote:


I just received the abstracts today. The CDC did two studies, one study on
diabetes and one on asthma. The asthma study is on a file and I will try to
get the diabetes abstract on file so I can send it by Email. The studies
represent pure junk science that is primarily propaganda .

The diabetes study looked at the hemophilus vaccine and diabetes. The
problem was that 94% of all people were receiving the vaccine, making it
impossible to properly study the effect of the vaccine. The immunization
rate was too high for them to repeat my finding. While I studied about
250,000 children in Finland the CDC studied only about 600 children. Half
of the children I studied did not receive vaccine.

The diabetes study also looked at the hepatitis B vaccine. The
immunization rate was only about 40% so it was possible to study the
effects I have seen. In fact they found that the group receiving the
hepatitis B vaccine after 2 months had a 50% increased risk of IDDM then
those receiving the vaccine at birth. Based on the data I have seen it
appears that their raw data indicates that vaccination after 2 months
increases the risk of diabetes. The CDC however manipulated the data by
using "fudge factors" . They mathematically decreased the risk of hepatitis
B vaccine on diabetes to compensate for more breast feeding in the diabetic
group. This decreases the apparent effect of the hepatitis B vaccine to
make it look as is if the vaccine, when given after 2 months, was
preventing diabetes when it was actually increasing the risk of diabetes.
This is completely unorthodox. I need more data to fully evaluate their
data set.

The asthma study, looked at the effect of the diphtheria, tetanus and
pertussis vaccines on asthma. Since almost every one in the HMO probably
received a diphtheria, tetanus and pertussis vaccine the study design is
worthless. They were probably comparing the acellular pertussis vaccine to
the whole cell pertussis vaccine (ie one possible toxin to another). They
found a slightly decreased risk of asthma with the whole cell pertussis
vaccine (ie increased risk with the acellular vaccine). This same finding
was noted recently in Sweden. It does not answer what is the effect of the
pertussis vaccine is compared to an unimmunized group. It also appears that
the oral polio vaccine has an increased risk, as opposed to the killed
polio, since all children would have received a polio vaccine. It does not
indicate the effect of an polio vaccine versus no polio vaccine. An rise of
10%, OR 1.10 is significant. If a child receives 10 vaccines and each
causes 10% of asthma or diabetes then all asthma and diabetes is caused by
vaccines.


Infant Vaccinations and Risk of Asthma in Childhood
F. DeStefano1, D. Gu2, P. Kramarz1
1CDC: Atlanta, GA; 2Emory Univ.: Atlanta, GA
Background: Recent small studies and theoretical considerations have raised
concern that certain vaccines, particularly pertussis, may increase the
risk of developing asthma. We evaluated this concern in an analysis of data
from the Vaccine Safety Datalink (VSD), a collaborative project between CDC
and four large health maintenance organizations (HMOs). Methods: During the
period from 1991 through 1996, we identified all children who were
continuously enrolled in the HMOs from birth until at least one year of
age. To ascertain children who developed asthma, we used computerized data
on medical care encounters for asthma or dispensings of asthma medications.
Vaccination history was obtained from automated immunization tracking
systems maintained by the HMOs. We used proportional hazards regression to
estimate relative risks of asthma. Date of first asthma diagnosis or
medication dispensing was the outcome of interest. Vaccination exposure was
defined as a time-dependent covariable according to the date of first dose
of a vaccine. The regression models were stratified by HMO and month of
birth and adjusted for gender, low birth weight status, socioeconomic
indicators, and the common infant vaccines. Results: The analysis involved
116,496 children, of whom 11,134 (10%) developed asthma. The risk ratio
(RR) of asthma associated with diphtheria, tetanus, and whole-cell
pertussis (DTP) vaccine was 0.96 (95% confidence interval, 0.85-1.10).
Receipt of oral polio vaccine (OPV) was highly correlated with DTP;
children who received OPV or DTP had a RR of 1.16 (0.91-1.47) relative to
children who received neither vaccine. For measles, mumps and rubella (MMR)
vaccine the RR was 1.00 (0.92-1.08). Conclusion: These results do not
support the hypothesis that DTP or MMR vaccine may increase children's risk
of developing asthma.





>> Vaccines do not cause diabetes, study finds
>> 2:20 a.m. ET (626 GMT) September 27, 1999
>>
>> SAN FRANCISCO, Sept 26 - Vaccines that protect against a common cause of
ear
>> infections, meningitis and chest infection, as well as against hepatitis
B,
>> do not seem to cause juvenile diabetes, researchers said on Sunday.
>>
>> They said their findings should answer worries voiced by anti-vaccine
>> groups, which have suggested that vaccines can cause the immune system
to go
>> awry, leading to autoimmune diseases such as juvenile diabetes.
>>
>> "I think that is an important finding,'' Dr. Barbara Murray of the
>> University of Texas at Houston told reporters at a meeting of infectious
>> disease experts hosted by the American Society for Microbiology.
>>
>> "This is not a huge concern, but once it is expressed it is usually
picked
>> up by others.''
>>
>> Anti-vaccine groups have fought against infant hepatitis B virus
>> immunisations, arguing in hearings held in Congress earlier this year
that
>> they can confuse the immune system.
>>
>> But a team at the Centres for Disease Control and Prevention (CDC) in
>> Atlanta found no link.
>>
>> The team looked at the diabetes registrations for three large health
>> maintenance organisations for all children born since 1988. They found
140
>> children with type-I or juvenile diabetes, caused when the immune system
>> attacks certain pancreatic cells.
>>
>> The researchers told the meeting that 94 percent of all children, those
with
>> diabetes and those without, had been vaccinated for Haemophilus
influenzae
>> type B (Hib) and about 40 percent against the hepatitis B virus.
>>
>> "Hib and hepatitis vaccines were not associated with an increased risk of
>> type-I diabetes,'' they told the meeting.
>>
>> The same team looked at 116,000 children, 11,000 of whom had asthma, and
>> found no suggestion that the common DTP (diphtheria, tetanus and
pertussis)
>> vaccine or measles, mumps and rubella vaccines caused asthma.

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