Deaths and drug citations
Vaccine death citations Drug adverse reactions citations
Gatnash AA, Connolly CK.Fatal chickenpox pneumonia in an
asthmatic patient on oral steroids and methotrexate.Thorax.
1995 Apr;50(4):422-3.PMID: 7785019; UI:
95304500
Kasper
WJ, Howe PM.Fatal varicella after a single course of corticosteroids.Pediatr Infect Dis J. 1990 Oct;9(10):729-32. No abstract available.PMID: 2235146;
UI: 91044642
Lantner
R, Rockoff JB, DeMasi J, Boran-Ragotzy R, Middleton E Jr.Fatal varicella
in a corticosteroid-dependent asthmatic receiving troleandomycin.Allergy
Proc. 1990 Mar-Apr;11(2):83-7.PMID: 2338242; UI: 90249721
Lake
KB, Browne PM, Van Dyke JJ, Ayers L.Fatal disseminated aspergillosis in
an asthmatic patient treated with corticosteroids.Chest. 1983
Jan;83(1):138-9. No abstract available.PMID: 6848318; UI: 83078373
Mallet
L, Mallet J. Ticlopidine and fatal aplastic anemia in an elderly woman.Ann Pharmacother. 1994 Oct;28(10):1169-71.PMID: 7841572; UI: 95143709
Omdal
R, Goransson L, Bergrem H.Fatal outcome of low-dose methotrexate therapy
in rheumatoid arthritis.Clin Rheumatol. 1993 Jun;12(2):283-4. No
abstract available.PMID: 8358998 [PubMed - indexed for MEDLINE]
Morice
AH, Lai WK.Fatal varicella zoster infection in a severe steroid
dependent asthmatic patient receiving methotrexate.Thorax. 1995
Nov;50(11):1221-2.PMID: 8553283; UI: 96149331
No
authors listed]Varicella-related deaths among adults--United States,
1997.MMWR Morb Mortal Wkly Rep. 1997 May
16;46(19):409-12.PMID: 9162840; UI: 97299946http://www.cdc.gov/mmwr/preview/mmwrhtml/00047618.htm
Riley
LC, et al Treatment-related deaths during induction and first remission of acute
myeloid leukaemia in children treated on the Tenth Medical Research Council Acute Myeloid
Leukaemia Trial (MRC AML10). Br J Haematol. 1999 Aug;106(2):436-444. [Record as supplied
by publisher] PMID: 10460604.
Between 1988 and 1995, 341 children with acute myeloid leukaemia (AML) were
treated on the Medical Research Council Acute Myeloid Leukaemia Trial (MRC AML10). The
5-year overall survival was 57%, much improved on previous trials. However, there were 47
deaths (13.8%), 11 of which were associated with bone marrow transplantation (BMT). The
treatment-related mortality was significant at 13.8%, but decreased in the latter half of
the trial from 17.8% in 1998-91 to 9.6% in 1992-95 (P = 0.03%). The main causes of death
were infection (65.9%), haemorrhage (19.1%) and cardiac failure (19.1%). Fungal infection
was a significant problem, causing 23% of all infective deaths. Haemorrhage occurred early
in treatment, in children with initial white cell counts >100 x 109/l (P = 0.001), and
was more common in those with M4 and M5 morphology. Cardiac failure only occurred from the
third course of chemotherapy onwards, with 78% (7/9) in conjunction with sepsis as a
terminal event. Some deaths could be prevented by identifying those most at risk, and with
prompt recognition and aggressive management of complications of treatment. Future options
include the prophylactic use of antifungal agents, and the use of cardioprotectants or
alternatives to conventional anthracyclines to decrease cardiac toxicity. PMID: 10460604
Silk
HJ, Guay-Woodford L, Perez-Atayde AR, Geha RS, Broff MD.Fatal varicella
in steroid-dependent asthma.J Allergy Clin Immunol. 1988
Jan;81(1):47-51.PMID: 3339190; UI: 88116368
Sy
ML, Chin TW, Nussbaum E.Pneumocystis carinii pneumonia associated with
inhaled corticosteroids in an immunocompetent child with asthma.J
Pediatr. 1995 Dec;127(6):1000-2. No abstract available.PMID: 8523172; UI: 96101729
Wolfromm
R, Herman D.Fatal varicella in a corticosteroid-dependent asthmatic
receiving troleandomycin.Allergy Proc. 1990
Mar-Apr;11(2):83-7.PMID: 2338242; UI: 90249721